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Insulinoma misdiagnosed as epilepsy

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Author(s): El Hadj Omar El Malki | Raouf Mohsine | Abdelkader Belkouchi | Ouadii Mouaqit | Ayman Boubouh | Lahcen Ifrine

Journal: Journal of Biophysical Chemistry
ISSN 2153-036X

Volume: 02;
Issue: 01;
Start page: 28;
Date: 2012;
Original page

Keywords: Insulinoma | Epilepsy | Convulsions | Hypoglycemia | Surgery

ABSTRACT
Insulinoma is a rare disease presenting with episodic neuroglycopenic and/or adrenergic symptoms. We describe the clinical case of a female subject, 44 years old, affected with insulinoma, misdiagnosed for two years as epilepsy, threaten with antiepileptics. Insuli-noma was diagnosed based on fasting blood glucose level of 15 mg/dl, high fasting immunoreactive insu-lin/blood glucose ratio (more than 0.3), and a tumor in the pancreas by abdominal CT. After surgical re-moval of the neoplasm, the blood glucose level and insulin level turned normal. A benign insulinoma was also confirmed by histopathological evaluation. The patient remained seizure-free during the 2-year follow up.
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