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Integrated Omics Analysis of Sjogren’s Syndrome

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Author(s): Jiye Ai | Sizhe Feng | Kaori Misuno | Shen Hu

Journal: Journal of Integrated OMICS
ISSN 2182-0287

Volume: 2;
Issue: 2;
Start page: 6;
Date: 2012;
Original page

Keywords: Omics | Proteomics | System Biology | Bioinformatics

ABSTRACT
Sjögren's syndrome (SS) is a chronic autoimmune disorder clinically characterized by dry mouth and eyes. The pathogenic mechanism of SS is inadequately understood and a long delay from the start of the symptoms to final diagnosis has been frequently observed. In this paper, we aim to provide an overview about using omics technologies to discover biomarkers for SS diagnosis and understand potential pathways underlying SS pathogenesis. Omics databases relevant to SS such as Sjögren’s Syndrome Knowledge Base, Saliva Ontology and SDxMart are also discussed.
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