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Intracranial hypertension after traumatic brain injury

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Author(s): Seppelt Ian

Journal: Indian Journal of Critical Care Medicine
ISSN 0972-5229

Volume: 8;
Issue: 2;
Start page: 120;
Date: 2004;
Original page

Keywords: Brain injury | cerebral perfusion | decompressive craniectomy | head injury | intracranial pressure

ABSTRACT
Traumatic brain injury is a devastating problem with both high mortality and high subsequent morbidity. Injury to the brain occurs both at the time of the initial trauma (the primary injury) and subsequently due to ongoing cerebral ischaemia (the secondary injury). Hypotension and hypoxaemia are well recognized causes of this secondary injury. In the intensive care unit raised intracranial pressure (intracranial hypertension) is seen frequently after a severe diffuse brain injury and leads to cerebral ischaemia by compromising cerebral perfusion. This paper reviews the pathophysiology of intracranial hypertension and summarises current and experimental approaches to its management in the intensive care unit.

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