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Intramedullary melanotic schwannoma

Author(s): Jason M. Hoover | Ravi Kumar | Jonathan M. Bledsoe | Caterina Giannini | William Krauss

Journal: Rare Tumors
ISSN 2036-3603

Volume: 4;
Issue: 1;
Start page: e3;
Date: 2012;
Original page

Keywords: schwannoma | spinal cord | melanin | neural crest

We present a case of an intramedullary melanotic schwannoma (IMS) of the thoracic spinal cord. To our knowledge, this is the seventh reported case of an IMS of the central nervous system. Schwannomas are benign nerve sheath tumors of neural crest origin composed entirely of well differentiated Schwann cells that typically occur in peripheral nerves. Both the intramedullary location and the melanotic component of the reported lesion make it exceedingly rare. We will present our case, theories as to the origin of these tumors, clues in radiographic identification, and current clinical follow-up recommendations.
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