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Investigation of Analgesic and Anti-inflammatory potential of ethanolic extract of Basella rubra

Author(s): J.P. Yanadaiah *1, S. Mohana lakshmi 2, Jayaveera. K.N 3, Sudhakar.Y 4, K. Ravindrareddy 1K. Mahesh Kumar 1

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 6;
Start page: 1775;
Date: 2011;
Original page

Keywords: Basella rubra | antiinflammatory | analgesic | flavanoids | glycosides.

Analgesic potential of ethanolic extract of Basella rubra was investigated on male swiss albino mice by hot plate, tail flick, tail immersion, tail clip and acetic acid induced writhing methods.Anti-inflammatory effect was tested on wistar rats using carragenan, dextran, histamine and cotton pellets as inducing agents. Results of EEBR were compared with the efficacy of standard analgesics and anti-inflammatory drugs. Alkaloids, glycosides, flavanoids, steroids etc were found in the extract in appreciable quantities, which may plausibly responsible for the activities studied.
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