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Investigation of Analgesic and Anti-inflammatory potential of ethanolic extract of Basella rubra

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Author(s): J.P. Yanadaiah *1, S. Mohana lakshmi 2, Jayaveera. K.N 3, Sudhakar.Y 4, K. Ravindrareddy 1K. Mahesh Kumar 1

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 6;
Start page: 1775;
Date: 2011;
Original page

Keywords: Basella rubra | antiinflammatory | analgesic | flavanoids | glycosides.

ABSTRACT
Analgesic potential of ethanolic extract of Basella rubra was investigated on male swiss albino mice by hot plate, tail flick, tail immersion, tail clip and acetic acid induced writhing methods.Anti-inflammatory effect was tested on wistar rats using carragenan, dextran, histamine and cotton pellets as inducing agents. Results of EEBR were compared with the efficacy of standard analgesics and anti-inflammatory drugs. Alkaloids, glycosides, flavanoids, steroids etc were found in the extract in appreciable quantities, which may plausibly responsible for the activities studied.
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