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Investigation of herbal oral contraceptive suspensions for its antisteroidogenic and antioxidant properties

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Author(s): T.Sundar Rajan | I.Sarathchandiran | B.Kadalmani

Journal: International Journal of Pharmacy and Biomedical Sciences
ISSN 0976-5263

Volume: 04;
Issue: 01;
Start page: 50;
Date: 2013;
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Keywords: Antisteroidogenic | Herbal oral contraceptive suspension | Antioxidant | Serum testosterone

ABSTRACT
Aim: The objective of the present study is to explore antisteroidogenic and antioxidant properties of herbal oral contraceptive suspension containing methanol extracts of Carica papaya leaves and Capparis aphylla aerial part. Method: The method mainly involves the oral administration of different doses of herbal oral contraceptive suspension (200, 300 and 400mg/kg b.w.) to rats, compared with a control group given with non herbal suspension containing only excipients. At the end of the study, various parameters such as testosterone levels, tissue biochemical, testicular enzymes and antioxidant levels were analyzed.Results: Finding of this study revealed the oral administration of extract at the dose of 200, 300 and 400mg/kg b.w. showed very significance (p
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