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INVITRO ANTIOXIDANT ACTIVITY OF VITEX NEGUNDO LINN BARK

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Author(s): Guguloth Sarvankumar | Vivekanandan Lalitha | Singaravel Sengottuvelu | Sheik Haja Sharif | Thangavel Sivakumar

Journal: International Research Journal of Pharmacy
ISSN 2230-8407

Volume: 2;
Issue: 11;
Start page: 105;
Date: 2011;
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Keywords: Anti-oxidant | Vitex negundo Linn bark.

ABSTRACT
The present study shows the Invitro antioxidant activity of methanolic extracts of Vitex negundo Linn bark (VBE). The methanolic extracts of Vitex negundo Linn bark results shows the significant Invitro anti oxidant activity in a concentration dependent manner. Free radicals are fundamentals to any biochemical process and represent an essential part of aerobic life and our metabolism. They are continuously produced by body’s normal usage of oxygen such as respiration and some cell mediated immune functions. The oxygen consumption inherent in cell growth leads to the generation of reactive oxygen species (ROS) (Gulcin et al., 2007). Most harmful effects are produced by the reactive oxygen species (ROS) in our body, ROS are act as oxidants. Antioxidants are the substances which scavenges the oxidation process. Antioxidants are a type of complex compounds found in our diet that act as a protective shield for our body against certain disastrous diseases such as arterial and cardiac diseases, arthritis, cataracts and also premature ageing along with several chronic diseases.
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