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Isolation, Characterization and Antimicrobial Activity of Butea monosperma (Lam.)

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Author(s): Chintan V Pandya | Chirag R Fultariya | Pravin H Parmar | B A Golakiya | Jignasu P Mehta

Journal: Iranian Journal of Pharmacology and Therapeutics
ISSN 1735-2657

Volume: 10;
Issue: 2;
Date: 2011;

ABSTRACT
Three flavonoids named (E)-3-(4-hydroxy-3-(3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H-pyran-2-yloxy) phenyl)-1-(2-hydroxy-4-(3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H-pyran-2-yloxy) phenyl) prop-2-en-1-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one, 2-(4-hydroxy-3-(3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H-pyran-2-yloxy) phenyl)-7-(3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H-pyran-2-yloxy) chroman-4-one, and one phenolic acid 3,4,5-trihydroxybenzoic acid were isolated from the flowers and roots of Butea monosperma (Lam.). Their structures were established based on various spectroscopic techniques. Isolated crude extract were subjected for antimicrobial activity against gram-positive and gram-negative bacteria, like Proteus vulgaris, Enterobacter aerogenosa, Pseudomonas, aeuroginosa and Escherichia coli gram-positive and Bacillus megatarium, Bacillus cerus and Bacillus subtilis gram-negative, using standard protocols with MIC (Bacterial) in range of 7.5 to 25 µg/ml and MIC (Fungal) in range of 10 to 300 µg/ml.

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