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Juvenile Churg-Strauss Syndrome as an Etiology of Myocarditis and Ischemic Stroke in Adolescents; a Case Report

Author(s): Mohammad-Hassan Moradinejad | Amir Rezaei | Vahid Ziaee

Journal: Iranian Journal of Pediatrics
ISSN 2008-2142

Volume: 21;
Issue: 4;
Start page: 530;
Date: 2011;
Original page

Keywords: Asthma | Churg-Strauss Syndrome | Vasculitis | Myocarditis | Stroke

Background: Churg-Strauss syndrome (CSS), a systemic vasculitis accompanied by asthma and eosinophilia, almost invariably affects the lung and is frequently associated with cutaneous involvement. It rarely has cardiac involvement. We report an unusual case of CSS with myocardial involvement and stroke."nCase Presentation: A 16-year old female suffered of allergic asthma for 4 years. She was under treatment with oral prednisolone and seretide inhalation. After CSS diagnosis, she developed paroxysmal atrial tachycardia. Serum levels of Troponin I and Troponin T were increased indicating massive myocardial damage probably due to myocarditis. After 5 months she developed acute hemiparesis without any evidence of ischemic or hemorrhagic event. She was treated with IVIg, intravenous pulses of methylprednisone and cyclophosphamide for each complication. "nConclusion: Myocarditis and stroke may also complicate CSS which should be taken in consideration for better management.

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