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Lectin receptors cytotopography of the mucous membrane of large intestine in

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Author(s): Radchuk O.M. | Beregova T.V. | Yashchenko A.M. | Ribal’chenko V.K.

Journal: Морфологія
ISSN 1997-9665

Volume: 3;
Issue: 4;
Start page: 71;
Date: 2009;
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Keywords: large intestine | «Apibact®» | «Omez®» | lectins | cytotopography

ABSTRACT
The aim of the research was to study the distribution of lectin receptors on the surface of the mucous membrane of large intestine of intact rats and to find out the kind of changes in their distribution in prolonged hypergastrinaemia and in introduction of multiprobiotics «Symbiter® acidophilic» and «Apibact®».. The research was carried out on 37 male white rats of Wistar line weighting 160-200 g. The rats received «Omez®» (reactant - omeprasolum) intraperitoneally in the dosage of 14 mg/kg once a day during 28 days. The data showed the specificity of lectin binding to the structural components of the wall of large intestine. In «Omez®» introduction we observed the changes of lectin receptors cytotopography of structural components of mucous, muscular and serous layers of large intestine. The group of animals receiving «Apibact®» and «Omez®» had the lectin receptors cytotopography similar to that of the control group with some differences. In the introduction of «Symbiter® acidophilic» and «Omez®» the lectin receptors cytotopography gradually approach to that of the control group.
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