Academic Journals Database
Disseminating quality controlled scientific knowledge

Lhermitte's Sign Developing after IMRT for Head and Neck Cancer

Author(s): Dong C. Lim | Patrick J. Gagnon | Sophia Meranvil | Darryl Kaurin | Linda Lipp | John M. Holland

Journal: International Journal of Otolaryngology
ISSN 1687-9201

Volume: 2010;
Date: 2010;
Original page

Background. Lhermitte's sign (LS) is a benign form of myelopathy with neck flexion producing an unpleasant electric-shock sensation radiating down the extremities. Although rare, it can occur after head and neck radiotherapy. Results. We report a case of Lhermitte's developing after curative intensity-modulated radiotherapy (IMRT) for a patient with locoregionally advanced oropharyngeal cancer. IMRT delivers a conformal dose of radiation in head and neck cancer resulting in a gradient of radiation dose throughout the spinal cord. Using IMRT, more dose is delivered to the anterior spinal cord than the posterior cord. Conclusions. Lhermitte's sign can develop after IMRT for head and neck cancer. We propose an anterior spinal cord structure, the spinothalamic tract to be the target of IMRT-caused LS.

Tango Rapperswil
Tango Rapperswil

     Affiliate Program