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Lichen planus – An update

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Author(s): Sanjeev B Gupta | N.D.Chaudhari | Aayush Gupta | H.V.Talanikar

Journal: International Journal of Pharmacy and Biomedical Sciences
ISSN 0976-5263

Volume: 04;
Issue: 02;
Start page: 59;
Date: 2013;
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Keywords: Lichen planus | Papules | Band like infiltrate in the upper dermis

ABSTRACT
Lichen planus (LP) is an idiopathic papulosquamous eruption of the skin, scalp, nails and mucous membranes characterized by the 4 p’s: purple, polygonal, pruritic, papules. It usually presents for the first time in the fourth to sixth decade. LP is thought to be immunologically mediated, though its pathogenesis is as yet uncertain. Histopathologic examination reveals compact orthokeratosis, Civatte bodies and a sharply defined band like infiltrate of lymphocytes in the upper dermis. LP usually resolves within 8-12 months and treatment primarily consists of topical and/or oral steroids that hasten recovery and give symptomatic relief. The disease usually heals by post inflammatory hyper or hypopigmentation especially in people of darker skin. Long term sequelae of LP are rare and it seldom recurs.

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