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Long-Term Outcome In Patients With Juvenile Idiopathic Arthritis

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Author(s): Amine Bouchra1, Ibn Yacoub Yousra1, Rostom Samira1, Abouqal Redouane2, Hajjaj-Hassouni Najia 1-2

Journal: Journal of Orthopaedics
ISSN 0972-978X

Volume: 7;
Issue: 3;
Date: 2010;
Original page

Keywords: long-term outcome | juvenile idiopathic arthritis | HAQ

ABSTRACT
Objective: To describe the long-term outcome of juvenile idiopathic arthritis (JIA) in Moroccan patients.Patients and methods:Cross-sectional study including patients with JIA according to the ILAR criteria for the diagnosis of JIA, old of more than 18 years, followed into hospital or consultation. The evaluation included a clinical evaluation (articular mobility, activity of the disease), functional estimation (HAQ) and structural analyze (Steinbrocker).Results:Fifty one patients were recruited (27 women and 24 men), of average age 27.60 years ± 7.35 [18-46]. Subtypes at inclusion were: 15% enthesitis related arthritis, 12% seronegative polyarthritis, 11% seropositive polyarthritis, 5% systemic arthritis, 5% oligoarthritis and 3% psoriatic arthritis. After on average 15.06 ± 8.88 years [3-39] disease onset, forty two patients (82.35%) had an active disease. Our patients had a disabled functional status with a median of HAQ higher than 1.0. Half of our patients had a stage III or IV of Steinbrocker. The pain visual analogue scale, health assessment questionnaire and erythrocyte sedimentation rate were significantly higher among patients having an active disease at the time of study. The duration of evolution and the delay of diagnosis were the major factors associated with a pejorative outcome at adulthood.Conclusion: This study showed that more than 80% of our Patients with JIA remained active at the adulthood and were generating of a disability and a structural destruction. The interest carried to the early treatment of the infantile diseases must also include, in our country, that of the JIA.J.Orthopaedics 2010;7(3)e9
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