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MARINE: THE ULTIMATE SOURCE OF BIOACTIVES AND DRUG METABOLITES

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Author(s): Jirge Supriya S | Chaudhari Yogesh S

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 1;
Issue: 1;
Start page: 55;
Date: 2010;
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Keywords: Marine flora and fauna | Secondary metabolites | Clinical trials | Symbionts

ABSTRACT
Bioactive compounds from marine flora and fauna have extensive past and present use in the treatment of many diseases and serve as compounds of interest both in their natural form and as templates for synthetic modification. Several molecules isolated from various marine organisms (microorganisms, algae, fungi, invertebrates, and vertebrates) are currently under study at an advanced stage of clinical trials, some of them have already been marketed as drugs. This article gives an overview of current trends in screening and the activity analysis of metabolites from marine resources. Although the marine resources have been somewhat limited to date, selected bioactive from marine flora and fauna have already published. This report summarizes the screening for bioactive compounds of marine animals and marine microorganisms. Finally, new approaches for the screening of metabolites from marine resources are discussed. The goal of this article is to expose the new models and mechanisms of action of marine substances to bring new solutions for tackling some of the major public health problems.
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