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Mean platelet volume in patients with acute pancreatitis

Author(s): Nigar Yılmaz | Orhan Veli Özkan2 | Sadık Büyükbaş | Yeşim Can | O.Hasan Öztürk | Akın Aydoğan | Zafer Yönden

Journal: Journal of Clinical and Experimental Investigations
ISSN 1309-8578

Volume: 2;
Issue: 4;
Start page: 362;
Date: 2011;
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Keywords: Acute pancreatitis | mean platelet volume | platelet count | platelet activation | inflammation

Objectives: Platelet contributed tissue damage and inflammations have been of increased interest. It was previously suggested that platelets have an important role in patients with acute pancreatitis (AP). We aimed to assess the mean platelet volume (MPV) which is described as an indicator of platelet activation and platelet count in patients with AP.Materials and methods: The study group consisted of 30 patients with AP and 30 control subjects who were matched for age, gender, body mass index (BMI). MPV values and platelet counts were measured on admission.Results: Mean platelet volume was significantly higher among patients with AP when compared with control group (8.82±1.33 vs. 7.94±0.54 fL respectively; p < 0.01). Platelet count was significantly lower among AP patients when compared with control group (223.0±46.2 vs. 295.3±58.9 ×109/L respectively; p < 0.001). The level of CRP was significantly higher in patients with AP compared with control group. Platelet and MPV were correlated with serum CRP levels in correlation analysis (p
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