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Methyl Prednisolone Injection Therapy For Unicameral Bone Cysts: A Comparative Study Between Upper And Lower Limb Cysts

Author(s): Sarrafan Nasser *, Mehdinasab Seyed abdolhossein* ,Pipelzadeh Mohammad Reza**

Journal: Journal of Orthopaedics
ISSN 0972-978X

Volume: 5;
Issue: 1;
Date: 2008;
Original page

Keywords: Unicameral bone cyst | methyl .prednisolone

Background:Unicameral bone cysts (UBC) are treated by several methods including curettage and bone graft, multiple drilling, autogenous bone marrow or corticosteroid injection into the bone cyst.UBC in lower extremity due to weight bearing can be complicated by pathologic fracture. Aim: The aim of this study was to assess and comparison the results of methyl prednisone injection in the UBC of the upper and lower limbs bone cyst. And compare outcome. Material and methods: 30 patients (12 girls 18 boys) with age group of 4.5-19 years old (mean 11.9) were treated by methylprednisolone injection into the bone cyst and were followed for 26-48 months (Average 32 months). Patients where evaluated by serial radiographs (AP & lateral) at 2-3 months intervals. Findings: UBC was located in humerus (n=18), in proximal of femur (n=9) and proximal of tibia (n=3). After methyl prednisolone injection into the lesion between 1-3 times, in 83 % of humerus cases and 44% femoral and 100% tibia bone cysts subsided and shrunk with increased bone density within 32 month. Conclusion:Injection of methylprednisolon into UBC is a simple therapeutic method with a low rate of morbidity. The favorable results were seen mostly in the UBC of the humerus and tibia a compared to the femoral bone.
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