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Microalbuminuria: relación con factores de riesgo cardiovasculares en pacientes diabéticos tipo 2

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Author(s): Ulises Leal | Milagros Espinoza | Santina Coccione | Eloina Peñate

Journal: Salus Online
ISSN 1316-7138

Volume: 14;
Issue: 3;
Start page: 49;
Date: 2010;
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Keywords: Microalbuminuria | cardiovascular risk factors | type 2 diabetes

ABSTRACT
The microalbuminuria (µAlb) represents an early sign of kidney lesion and a general marker of endothelial damage, which increases to the extent that this baseline hyperglycemia or type 2 diabetes mellitus. The µAlb was significantly associated with the premature death of cardiovascular origin, rather than the progression of end-stage renal damage. The objective of this research was to relate intype 2 diabetics different cardiovascular risk factors with the presence of µAlb. This was a descriptive, cross sectional, that included 224 patients with an age range between 37 and 88 years (58.4 ± 9.8 years), of which 127 (56.7%) had µAlb and 26.7% of they were also treated hypertensives. No significant difference when comparing glycemic control among diabetics with µAlb (6.8 ± 1.17%) and without µAlb (6.4 ± 3.04%).The time course of the disease was between 5 to 10 years (58%) and the prevalence of metabolic syndrome (MetS) was observed by 48%. It showed significant association between the µAlb and abdominal circumference (AC), systolic blood pressure, body mass index, total cholesterol, HDL cholesterol, triglycerides, and MetS. Of these factors, the most influential variable for the presence of µAlb was the AC. It reiterates the inclusion in the clinical practice of determining uAlb in patients with type 2 diabetes, as a marker of cardiovascular risk and according to the results of the regression model further benefit diabetic with abdominal obesity uAlb
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