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Microanatomical Study of the Maternal Diabetes Effects on Rat`s Choroids Plexus in Embryonic, Neonatal and Adulthood Stages

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Author(s): M. Tehranipour

Journal: Journal of Biological Sciences
ISSN 1727-3048

Volume: 8;
Issue: 7;
Start page: 1199;
Date: 2008;
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Keywords: Angiogenesis | maternal diabetes | choroids plexus | developmental

ABSTRACT
In this research, the effect of maternal diabetes on the choroids plexus volume changes and total length of capillaries in (15°, 1-day-old and 30-day-old) rat neonates was studied. Diabetes was induced by streptozotocin (60 mg kg-1), given by a single intraperitoneal injection to female Wistar rats (250-300 g). Control animals were given an equivalent amount of citrate buffer saline. In three stage of life, the volume of choroids plexus and total length of capillaries by stereological methods was measured. Statistical analysis`s showed significant difference in choroids plexus volume and total length of capillary`s between diabetic and control groups (p
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