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Microinvasive cervical cancer in pregnancy

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Author(s): Mladenović-Segedi Ljiljana | Novaković Petar | Mandić Aljoša | Mihajlović Olgica | Ivković-Kapicl Tatjana

Journal: Archive of Oncology
ISSN 0354-7310

Volume: 13;
Issue: 3-4;
Start page: 145;
Date: 2005;
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Keywords: pregnancy | cervix neoplasms | diagnosis | neoplasm staging | treatment outcome

ABSTRACT
Cervical cancer is the most frequently diagnosed malignant disease in pregnancy. The clinical symptoms are scarce or none. The diagnosis is made primarily with a cervical smear, as well as a colposcopic examination and directed cervical biopsy. The treatment of cervical cancer depends on the stage of the disease, the gestation period, and a patient’s wish to carry a pregnancy to term. The illustrated case is of a patient who with the diagnosed presence of microinvasive squamous cell cancer, due to cervical biopsy, in the 1st trimester of pregnancy. In the 2nd trimester, diagnostic conization was performed in order to exclude the presence of the invasive disease. The definite histopathologic findings indicated the presence of cancer in situ. The conization margins were negative and thus the patient was successfully cured. The patient had a cesarean birth in the 36th week of pregnancy and she gave birth to an alive female newborn. Women are given the chance to have cervical cancer diagnosed and treated in the early stages of pregnancy owing to the introduction of a cervical smear in the modern protocol of antenatal protection.
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