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Molecular and biochemical studies on bovine ephemeral fever

Author(s): Nahed S. Thabet; Emad W. Ghazy; Mohamed A. Nayel; Mohamed Abo-Elkhair

Journal: Research Opinions in Animal & Veterinary Sciences
ISSN 2221-1896

Volume: 1;
Issue: 5;
Start page: 269;
Date: 2011;
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Keywords: Bovine Ephemeral Fever | Molecular | Biochemical | Hypocalcemia

Bovine ephemeral fever (BEF) in cattle has been reported to be associated with a range of biochemical changes which are similar to those seen in milk fever. This study aimed to clarify the biochemical alterations that associate infection of cattle with BEF with special references to the mechanisms involved in the development of hypocalcemia. The study was conducted on 30 cases of cattle infected with BEF based on the characteristic clinical signs which were confirmed by isolation of virus and RT-PCR. Another 6 healthy cows were used in the study as control. The evaluated parameters included biochemical variables such as serum values of total protein (TP), albumin (Alb), glucose (Glu), total calcium (tCa), ionized calcium (iCa), inorganic phosphorus (P), magnesium (Mg), sodium (Na), potassium (K), chloride (Cl), creatinine (Cr), blood urea nitrogen (BUN) and serum activity of alkaline phosphatase (ALP). Hormonal profile included parathyroid hormone (PTH), insulin (Ins), and cortisol (Cor). The results showed that BEF-infected animals demonstrated a significant decrease (P
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