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Monitoramento de eventos adversos em ambiente hospitalar: relato de farmacovigilância, São Paulo

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Author(s): Fabiana Gatti de Menezes | Jorge Willian Leandro Nascimento

Journal: ConScientiae Saúde
ISSN 1677-1028

Volume: 9;
Issue: 4;
Start page: 582;
Date: 2010;
Original page

ABSTRACT
Introduction: According to PAHO/WHO, the hospital admissions¿ due to adverse drug reactions (ADR) in some countries is around 10%, resulting in additional costs for health system. Objective: To determine which drugs are involved in adverse drug reactions and the most common reactions. Methods: We conducted a descriptive monitoring of ADR in a private hospital in São Paulo (Brazil), from 2004 to 2008, in 197 beds, totaling 100 notifications. Data described in frequency (n ADR reported). Results: The drugs most commonly involved in ADR were cephalosporins (13%) and quinolones (12%). The adverse reactions were rash (20%), pruritus (13%), redness (12%), nausea (10%), tremors (9%), erythemtous plaques (6%), etc. We observed that 61% of individuals with ADR are female. Conclusion: Achieve the development of positive attitude towards pharmacovigilance among healthcare professionals to ADR becomes accepted and understood. There was an increase in notifications, antibiotics are involved in ADR and female have more ADR.

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