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Morphological and clinical features of small cava septi pellucidi: a post mortem study

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Author(s): Filipovic BR | Jovic NJ | Filipovic BF | Ilankovic AN | Ilankovich NN

Journal: Neuroanatomy
ISSN 1303-1783

Volume: 5;
Issue: 1;
Start page: 8;
Date: 2006;
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Keywords: septum pellucidum | cavum | schizophrenia | alcoholism | head trauma

ABSTRACT
Small cava septi pellucidi (CSP) are sometimes automatically regarded as an anatomical variation (asymptomatic CSP), especially if they could not be associated with a neuropsychiatric disorder, like schizophrenia or alcoholism (symptomatic CSP). Our aim was to investigate the impact of symptomatic CSP in the population in which CSP length was less or equal to 6 mm (criterion established by Nopoulos et al in 1997). We have overlooked 479 post mortem brains that underwent serial frozen sections in the axial plane on 1.5 mm of thickness. A sample of 110 CSP was obtained, among which 50 were adequate for this study. In our sample, 26 CSP were asymptomatic, 13 were on alcoholic brains, 6 were obtained from subjects who faced one or several head trauma and later manifested aggressive behavior, and remaining 5 belonged to schizophrenics. There were no major differences in lengths and widths measured, except between the lengths of CSP in schizophrenics and alcoholics (p

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