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Movement disorder: A manifestation of HIV and its response to therapy

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Author(s): Sankhla Charulata | Soman Rajeev | Gupta Neha | Shah Pratik

Journal: Neurology India
ISSN 0028-3886

Volume: 57;
Issue: 6;
Start page: 789;
Date: 2009;
Original page

Keywords: Anti-retroviral therapy | human immunodeficiency virus | movement disorder

ABSTRACT
Both akinetic and hyperkinetic movement disorders may rarely be the presenting feature of human immunodeficiency virus (HIV) infection. The possible pathogenic basis is the involvement of subcortical structures by the HIV infection-related pathology. Opportunistic infections, or mass lesions complicating HIV infection. In addition dopaminergic dysfunction and medications may also play a role. We report a HIV infected male who presented with progressive choreoathetoid movements and dystonia. He had remarkable improvement of the movement disorder with tetrabenazine and anti-retroviral therapy (HAART) treatment.
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