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Nasal extranodal NK/T-cell lymphoma presenting as a perforating palatal ulcer: A diagnostic challenge

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Author(s): Patel Vidula | Mahajan Sunanda | Kharkar Vidya | Khopkar Uday

Journal: Indian Journal of Dermatology, Venereology and Leprology
ISSN 0378-6323

Volume: 72;
Issue: 3;
Start page: 218;
Date: 2006;
Original page

Keywords: Chemotherapy | Lymphoma | Palatal ulcer

ABSTRACT
A 40-year-old man presented with chronic nasal stuffiness and bloodstained discharge of 3 years′ duration, along with a non-healing palatal ulcer since 2 months. Examination revealed a perforation in the midline on the hard palate and a superficial ulcer on the soft palate. Histopathology and immunohistochemistry suggested a diagnosis of extranodal nasal/nasal-type T-cell lymphoma. The patient was started on multiagent chemotherapy in the form of cyclophosphamide, doxorubicin, vincristine and prednisolone but succumbed after two cycles. Only one case of nasal T cell lymphoma presenting as nasal septal perforation, oronasal fistula and a concomitant palatal ulcer has been described. We report this case of a perforating palatal ulcer as a rare presentation of nasal lymphoma.
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