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Nasilenie objawów depresji mierzone za pomocą Skali depresji Hamiltona oraz manii mierzone za pomocą Skali manii Younga w stanie mieszanym w przebiegu choroby afektywnej dwubiegunowej

Author(s): Iwona Koszewska | Anna Chojnacka | Jarosław Torbiński | Łukasz Święcicki | Dorota Bzinkowska | Sławomir Fornal | Aleksandra Kucharska | Janusz Rybakowski

Journal: Neuropsychiatria i Neuropsychologia
ISSN 1896-6764

Volume: 3;
Issue: 1;
Start page: 7;
Date: 2008;
Original page

Keywords: bipolar disorder | mixed episode | Hamilton Depression Rating Scale | Young Mania Rating Scale

Study aim: The diagnosis of mixed episodes in the courseof bipolar affective illness is made on the basis ofclinical examination, so it may pose a challenge to cliniciansdue to the lack of standard assessment tools. Theaim of the study was to assess the utility of the HamiltonDepression Rating Scale (HDRS) and Young ManiaRating Scale (YMRS) for the diagnosis of mixed episodesin the course of bipolar disorder.Material and methods: The study included a group ofpsychiatric inpatients (n=75) diagnosed with bipolaraffective disorder (ICD 10 criteria). The patients werebeing treated for depressive episodes (n=46), manic episodes(n=13) or mixed episodes (n=12). The assessmentof the symptoms was made at the beginning of hospitalizationusing HDRS and YMRS.Results: It was found that during mixed episodes theintensity of depressive and manic symptoms was similar(HDRS 14.4±7.4 vs. 13.3±8.2 in YMRS). The intensityof manic symptoms during depressive episodes wasmean 9.3 pts. (±10 SD); mainly sleep disturbances andirritability. The intensity of depressive symptoms duringmanic episodes was mean 7.4 pts. (±4.4 SD); mainlysleep disturbances, agitation and restlessness.Conclusions: The results showed that both HDRSand YMRS may be useful in the diagnosis of mixedepisodes. Common symptoms of manic and depressivestates do not constitute a significant limitation ofthese tools.
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