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Non oncologic elevated levels of chromogranin A in a symptomatic patient without a carcinoid tumor

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Author(s): Juan Camilo Duque | Luis Fernando Pineda | Tatiana Lopez

Journal: Endocrinology Studies
ISSN 2038-9515

Volume: 3;
Issue: 2;
Start page: e7;
Date: 2013;
Original page

Keywords: neuroendocrine tumors | chromogranin A | somatostatin analogues

ABSTRACT
The diagnosis of neuroendocrine tumors requires a highly suspicious level due to its variable symptoms and clinical presentation. Early diagnosis, prompt and appropriate treatments are clues to success preventing the eventual disease progression and the devastating consequences of the carcinoid syndrome. Measurement of the chromogranin A, plays an important role in the diagnosis of carcinoid tumors, during the clinical evolution and even more to evaluate the treatment response to somatostatin analogues. However, in some situations like our case, the serum levels evaluation could be a confounding factor imitating the clinical scenario of the disease especially when the chromogranin level is elevated but not in the typical oncologic range and moreover when the symptoms magnitude is really convincing and similar to the tumor disease instances.
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