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A Novel Antibacterial Dental Resin Composite

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Author(s): Yiming Weng | Voon J. Chong | Leah Howard | Ruijie Huang | Richard L. Gregory | Dong Xie

Journal: Journal of Biomaterials and Nanobiotechnology
ISSN 2158-7027

Volume: 03;
Issue: 02;
Start page: 130;
Date: 2012;
Original page

Keywords: Furanone Derivative | Antibacterial | Resin Composite | CS | S. mutans Viability

ABSTRACT
This study reports the synthesis and evaluation of a novel furanone-containing antibacterial resin composite. Compres-sive strength (CS) and S. mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. With 5% to 30% addition of the furanone derivative, the composite showed no change in CS but a significant antibacterial activity with a 16% - 68% reduction in the S. mutans viability. Further, the antibacterial activity of the modified composite was not affected by human saliva. The aging study implies that the modified composite may have a long-lasting antibacterial function. Within the limitations of this study, it appears that this experimental resin composite may potentially be developed into a clinically attractive dental restorative due to its high mechanical strength and antibacterial function.
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