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Olive and Corn Oil Enriched Diets Changed the Phospholipid Fatty Acid Composition in Mice Liver after One-Thirds Hepatectomy

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Author(s): Mira Cuk | Biserka Radosevic Stasic | Cedomila Milin | Jasminka Giacometti | Alena Buretic Tomljanovic

Journal: Advances in Molecular Imaging
ISSN 2161-6728

Volume: 03;
Issue: 02;
Start page: 240;
Date: 2012;
Original page

Keywords: Fatty Acids | Phospholipids | One-Thirds Partial Hepatectomy | Olive Oil | Corn Oil | Diet

ABSTRACT
We examined the effect of dietary fats on the kinetics of liver regeneration after one-third partial hepatectomy (PH) in male Balb/c mice. Corn and olive supplemented diets were chosen as a model of n-6 and n-9 diets. Phospholipid fatty acids were determined by gas chromatography (GC) after previous fractionation by solid-phase extraction using aminopropyl (NH2) column, and data were analysed by nonparametric Kruskal-Wallis test. Diet enriched with corn and olive oil did not affect the balance of lipid disorders during liver regeneration after 1/3 PH. Desaturases activity direction has changed depending on the used diet. The key role in the alteration of the polar fatty acids profile at all stages of liver regeneration and examined dietary fats is played by activity of stearoyl-CoA desaturase (SCD).
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