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Oncogenic osteomalacia: Problems in diagnosis and long-term management

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Author(s): Dhammi Ish | Jain Anil | Singh Ajay | Mishra Puneet | Jain Saurabh

Journal: Indian Journal of Orthopaedics
ISSN 0019-5413

Volume: 44;
Issue: 4;
Start page: 453;
Date: 2010;
Original page

Keywords: Oncogenic osteomalacia | mesenchymal tumor | hypophosphatemic osteomalacia

ABSTRACT
Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the lesion responsible for producing the osteomalacia is excised. For a clinical diagnosis a high index of suspicion is necessary. We present three such cases where in one the oncogenic osteomalacia reversed while in rest it did not. We present this case report to sensitize about the entity.
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