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Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report

Author(s): Aragão AnaLuizaAndrade | Silva IvaniNovato

Journal: International Journal of Pediatric Endocrinology
ISSN 1687-9848

Volume: 2010;
Issue: 1;
Start page: 432060;
Date: 2010;
Original page

Polyostotic fibrous dysplasia (FD) associated to McCune-Albright Syndrome (MAS) often leads to fractures, deformities, and bone pain resulting in bad quality of life. Parenteral bisphosphonates have been used in children and adolescents to improve these symptoms with few adverse effects. We evaluated the response to oral Alendronate in a girl with severe MAS FD and observed improved quality of life with reduction of bone pain.
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