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Organoprotective effects of the fixed combination of angiotensin-converting enzyme inhibitor lisinopril and diuretic hydrochlorothiazide

Author(s): E.A. Ryabikhin | M.E. Mozheiko

Journal: Racionalʹnaâ Farmakoterapiâ v Kardiologii
ISSN 1819-6446

Volume: 5;
Issue: 6;
Start page: 25;
Date: 2009;
Original page

Keywords: arterial hypertension | lisinopril | hydrochlorothiazide.

Aim. To study effects of fixed drug combination of lisinopril and hydrochlorothiazide – Listril® Plus (Dr. Reddy’s laboratories), on blood pressure (BP), morphofunctional indexes of left ventricle, elastic features of the main arteries and quality of life in patients with arterial hypertension (HT).Material and methods. 30 patients with HT of 1-3 degree (aged 70,5±2, y.o., HT duration 14,8±1,8 years) received the drug within 12 weeks.Results. Office BP reduced from 161,8±18,6/93,9±8,9 mm Hg to 137,3±12,2/84,1±6,5 mm Hg (p
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