Academic Journals Database
Disseminating quality controlled scientific knowledge

Osteopoikilosis: A Sign Mimicking Skeletal Metastases in a Cancer Patient

ADD TO MY LIST
 
Author(s): Sepideh Sefidbakht | Yaghoub Ashouri-Taziani | Sareh Hoseini | Mansour Ansrai | Niloofar Ahmadloo | Ahmad Mosalaei | Shapour Omidvari | Hamid Nasrolahi | Mohammad Mohammadianpanah

Journal: Middle East Journal of Cancer
ISSN 2008-6709

Volume: 2;
Issue: 1;
Start page: 37;
Date: 2011;
VIEW PDF   PDF DOWNLOAD PDF   Download PDF Original page

Keywords: Osteopoikilosis | Osteosclerotic | Skeletal metastases | Breast cancer.

ABSTRACT
Osteopoikilosis is a rare benign osteosclerotic bone disorder that may be misdiagnosed as skeletal metastases. Here we describe a case of coincidental breast cancer and osteopoikilosis mimicking skeletal metastases. A 41-year-old woman underwent right modified radical mastectomy in April 2007. Twenty-eight months after initial treatment,the patient complained of bilateral knee and foot pain. Plain X-rays of the feet and knees showed multiple well-defined osteosclerotic lesions. According to the radiographic appearance, the most likely differential diagnoses included skeletal metastases from breast cancer and osteopoikilosis. A whole-body bone scintigraphy showed no increase in uptake by the sclerotic lesions, and serum lactic dehydrogenase, carcinoembryonic antigen, alkaline phosphatase and cancer antigen 15-3 were not elevated. We therefore diagnosed the patient’s skeletal lesions as osteopoikilosis. This case and ourliterature review suggest that the radiographic appearance of osteopoikilosis may mimic or mask skeletal metastases, potentially leading to misdiagnosis in patients with cancer.
Why do you need a reservation system?      Save time & money - Smart Internet Solutions