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Osteosarcoma of maxilla: a case of missed initial diagnosis

Author(s): Antony George | Varghese Mani | S.Sunil | B.S.Sreenivasan | Devi Gopakumar

Journal: Oral & Maxillofacial Pathology Journal
ISSN 0976-1225

Volume: 1;
Issue: 1;
Start page: 33;
Date: 2010;
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Keywords: bone tumors | osteosarcoma | osteogenic sarcoma | chondroblastic | jaw | maxilla.

Primary neoplasms of human skeleton are rare, accounting for 0.2% of overall humantumor burden. Osteosarcoma accounts for 15-35% of all primary bone tumors. Whileosteosarcoma of jaw bones are even rarer, representing 4-8% of all osteosarcomas. Peakincidence for jaw osteosarcoma is 3rd-4th decade, while osteosarcomas of long bones show abimodal age distribution. Here we report an unusual case history of a 54yrs old male withswelling in anterior gingiva of maxilla with mobility of teeth, which on x-ray was defined as noncontributory,and on incisional biopsy was diagnosed as giant cell granuloma. However onhistopathological examination after wide surgical excision, it showed large areas of lobularmalignant cartilage with few areas of disorganized tumor osteoid and atypical spindle cells, andwas reported as chondroblastic osteosarcoma.
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