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Oxidative stress in patients on mechanical ventilation

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Author(s): Marjanović Vesna | Đorđević Vidosava | Marjanović Goran

Journal: Medicinski Pregled
ISSN 0025-8105

Volume: 62;
Issue: 11-12;
Start page: 578;
Date: 2009;
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Keywords: Oxidative Stress | Respiration | Artificial | Lipid Peroxides + blood | Blood-Air Barrier | Pulmonary Gas Exchange

ABSTRACT
Introduction. The appearance and intensity of oxidative stress were analyzed in the course of mechanical ventilation and parameters that could point toward potential lung damage. Material and methods. In three time intervals on day 1, 3 and 7 of mechanical ventilation, parameters such as: triglycerides, cholesterol, lactate, serum lactic dehydrogenase, acid-base balance and lipid peroxidation products - thiobarbituric acid reactive substances, were followed in 30 patients with head injuries. Results. A decrease in the level of partial oxygen pressure (PaO2) (p

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