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"PATHOLOGIC FRACTURE OF THREE EXTREMITIES AS FIRST SIGN OF ACUTE LYMPHOBLASTIC LEUKEMIA "

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Author(s): S. Al-Yasin | S. H. Nabavizadeh | M. Nabavi | M. Kiani | M. Safari O. Zekavat

Journal: Acta Medica Iranica
ISSN 0044-6025

Volume: 45;
Issue: 1;
Start page: 83;
Date: 2007;
Original page

Keywords: multiple fracture | radiologic finding

ABSTRACT
Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer representing 80-85% of all leukemia. We describe a 3 years old girl with pain, swelling and tenderness in extremities since 8 months prior to her present admission. X-ray of extremities revealed callus formation, osteopenia and site of healed fractures. Bone marrow aspiration revealed ALL-L2 with normal peripheral smear. It is important for physician to recognize the skeletal manifestations of acute leukemia of childhood because a delay in diagnosis has an adverse effect on survival.
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