Academic Journals Database
Disseminating quality controlled scientific knowledge

PATTERN OF INHERITANCE OF IDIOPATHIC HYPERCALCIURIA IN TWO FAMILIES

ADD TO MY LIST
 
Author(s): A. Nickavar | M. Sharifian A. Tabarroki

Journal: Acta Medica Iranica
ISSN 0044-6025

Volume: 44;
Issue: 6;
Start page: 357;
Date: 2006;
Original page

Keywords: Idiopathic hypercalciuria | inheritance

ABSTRACT
Idiopathic hypercalciuria is a leading cause of frequency-dysuria syndrome in childhood. Different modes of inheritance have been suggested in this disease. This article presents the occurrence of idiopathic hypercalciuria in all children of two families. In the first family, a 5.5 year old girl with a history of renal stones and dysuria due to hypercalciuria, had two involved brothers and one sister. In the second family, hypercalciuria and medullary nephrocalcinosis were detected in two siblings who were admitted for polyuria and dysuria. Idiopathic type of hypercalciuria was diagnosed in these two families by normal laboratory exams and exclusion of other causes of normocalcemic hypercalciuria. According to the involvement of all offsprings (both sexes) in these two families, it is suggested that idiopathic hypercalciuria is an autosomal dominant disease with complete penetration.
Affiliate Program      Why do you need a reservation system?