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Persistent Hyperprolactinemia and Bilateral Galactocele in a Male Infant

Author(s): Paolo A. Tomasi | Giuseppe Fanciulli | Tiziana Casti | Giuseppe Delitala

Journal: International Journal of Pediatric Endocrinology
ISSN 1687-9848

Volume: 2009;
Date: 2009;
Original page

Galactocele is a benign breast lesion, usually occurring in nursing women. This lesion is a rare cause of breast enlargement in children. In this paper we describe the case of an infant with hyperprolactinemia (which persisted throughout 15 years of clinical observation) and bilateral galactocele. We speculate that a congenital midline defect in our patient might have impaired the normal dopaminergic inhibitory tone on pituitary lactotroph cells, thus leading to an increased prolactin secretion by the pituitary gland; this, in turn, might have favored the development of the galactocele.
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