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The perspectives of adjunctive drugs usage in the treatment of glucose metabolism disturbances in adolescent patients

Author(s): Ewa Otto-Buczkowska | Łukasz Machnica

Journal: Pediatric Endocrinology, Diabetes and Metabolism
ISSN 2081-237X

Volume: 15;
Issue: 4;
Start page: 260;
Date: 2009;
Original page

Keywords: glucose metabolism disturbances | diabetes control criteria | basic treatment | adjunctive drugs

Tightening of the diabetes control criteria in the last few years induces searches for adjunctive drugs to reinforce the basic treatment typical for the specific type of the disease. These agents are meant to stimulate insulin secretion, increase insulin sensitivity or inhibit the antagonists of the hormone. Up till now that kind of studies included adults, mainly with type 2 diabetes. Nowadays, however, the increasing number of research focuses on type 1 diabetic patients. The attempts to introduce this type of treatment in adolescent patients encounter many limitations, mostly of formal nature due to drug registration requirements. Nevertheless, more and more studies point at the efficacy of these agents and the possibility of their usage also in adolescents with different types of diabetes.
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