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PHYTOCHEMICAL STUDIES AND ANTIHELMINTHIC ACTIVITY OF GYMNEMA SYLVESTRE

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Author(s): Kethireddy Sravani | J. Ramya | A. Pradeep Kumar | V. Asha Jyothi

Journal: International Journal of Research in Ayurveda and Pharmacy
ISSN 2229-3566

Volume: 2;
Issue: 3;
Start page: 931;
Date: 2011;
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Keywords: Gymnema sylvestre | Antihelminthic activity | Albendazole.

ABSTRACT
Helminthes are the parasitic threat to the man. Many synthetic anti helminthic agents have been identified so far, the major disadvantages with these agents are their side effects. Drugs from natural sources are giving an edge to combat parasitic problems with minimal side effects and better pharmacological action than the synthetic agents. Many agents from natural sources have been identified and many are yet to be explored in this area. In the present study, Gymnema sylvestre was selected based on ancient literature and are subjected to scientific pharmacological screening on Pheretima posthuma for anti helminthic activity. The ethanolic extract of the plant was found to have significant anti helminthic activity. Except Chloroform extract all groups of other extracts i.e., Ethanolic, Methanolic and Petroleum Ether extract have significance with the Standard drug (Albendazole) *(p
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