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Piper betle L.: A review on its ethnobotany, phytochemistry, pharmacological profile and profiling by new hyphenated technique DART-MS (Direct Analysis in Real Time Mass Spectrometry).

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Author(s): Kushagra Nagori*, Mukesh Kumar Singh, Amit Alexander, Tekeshwar Kumar, Dhansay Dewangan, Hemant Badwaik, D.K. Tripathi

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 9;
Start page: 2991;
Date: 2011;
Original page

Keywords: P.betle | DART-MS | creeper | antioxidant | chavibetol.

ABSTRACT
The Piper betle plant is an evergreen and perennial creeper which is used in several traditional medicines to cure various diseases. This plant has been knownto possess antioxidant, antifungal, antiulcerogenic, antiplatelet, antidiabetic, immunomodulatory, antileishmanial, antiamoebic, anti-inflammatory, antifilarialand antimicrobial activity. A wide range of chemical compounds including chavibetol, allyl pyrocatechol, eugenol, quercetin, caryophyllene, safrole,hydroxychavicol, a-pinene, myrcene, chavicol, Germacrene-D, a- terpineol , ß-pinene, camphene etc have been isolated from this plant. The present reviewsummarizes the information concerning the botany, ethnopharmacology, phytochemistry, biological activity and use of hyphenated analytical technique likeDART-MS (Direct Analysis in Real Time Mass Spectrometry) and other techniques for characterizing various compounds from P. betle plant.
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Tangokurs Rapperswil-Jona