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Positron emission tomography / computerized tomography evaluation of primary Hodgkin′s disease of liver

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Author(s): Gota V | Purandare N | Gujral S | Shah S | Nair R | Rangarajan V

Journal: Indian Journal of Cancer
ISSN 0019-509X

Volume: 46;
Issue: 3;
Start page: 237;
Date: 2009;
Original page

Keywords: Hodgkin′s lymphoma | primary hepatic lymphoma | positron emission tomography / computerized tomography

ABSTRACT
Occurrence of primary Hodgkin′s lymphoma (PHL) of the liver is extremely rare. We report on a case of a 60-year-old male who presented with liver mass and B-symptomatology. Hepatoma or hepatic metastasis from a gastrointestinal primary was initially suspected. Tumor markers like AFP, CEA, Total PSA, and CA-19.9 were within normal limits. Positron Emission Tomography / Computerized Tomography (PET/CT) revealed a large hepatic lesion and a nodal mass in the porta hepatis. A liver biopsy was consistent with Hodgkin′s lymphoma. There was complete regression of the hepatic lesion and evidence of shrinkage of the nodal mass following four cycles of chemotherapy. 18F Fluro -de-oxy Glucose (FDG) PET / CT in this case helped in establishing a primary hepatic lymphoma by demonstrating the absence of pathologically hypermetabolic foci in any other nodes or organs. PET / CT scan is a useful adjunct to conventional imaging and histopathology, not only to establish the initial diagnosis, but also to monitor treatment response in PHL.
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