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Possible Reversal of Sodium Arsenate-induced Liver Toxicity by Hexane Leaf Extract of Alchornea laxiflora

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Author(s): Uhunmwangho S. Esosa | Omage Kingsley | Erifeta O. Georgina | Josiah J. Sunday | Nwangwu C.O. Spencer

Journal: Asian Journal of Medical Sciences
ISSN 2040-8765

Volume: 5;
Issue: 1;
Start page: 3;
Date: 2013;
Original page

Keywords: Alchornea laxiflora | hexane | liver homogenate | serum enzymes | sodium arsenate | toxicity

ABSTRACT
This research was aimed at evaluating the anti-toxicity potentials or properties of A. laxiflora Thus, the possible reversing effect of sodium arsenate-induced liver toxicity by hexane leaf extract of Alchornea laxiflora was investigated using adult wistar albino rats weighing between 150-200 g as experimental model. Oral administration of the extract at varying doses (0.5, 1.0, 5.0 and 10.0 mg/kg body weight) was shown to significantly (p
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