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Preclinical studies on the Phytochemical, Antimicrobial, and Wound healing properties of Indigofera aspalathoides leaves

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Author(s): Subhashini. S 1, Kantha D. Arunachalam 2* Sathesh Kumar A.2

Journal: Journal of Pharmacy Research
ISSN 0974-6943

Volume: 4;
Issue: 9;
Start page: 3206;
Date: 2011;
Original page

Keywords: Indigofera aspalathoides | phytochemical analysis | antimicrobial activity | antiradiation activity | wound healing activity.

ABSTRACT
Indigofera aspalathoides has been used in Ayurvedic formulations in ancient India. In order to study and evaluate the phytochemical activity of Indigoferaaspalathoides, five different solvents methanol, ethanol, ethyl acetate, chloroform and hexane extracts were used for the extraction of the active ingredientsfrom the plant leaves. The study of antioxidant, antimicrobial, and wound healing activities were done using the methanolic extract. Excision wound model onSwiss albino mice was used to assess the wound healing activity of the leaves. Remarkable wound healing activity was observed with the ointment formulation ofthe methanol extract at 1% concentration. The results of our preclinical studies in mice demonstrated that the leaves of Indigofera aspalathoides possessantioxidant and antimicrobial activity and wound healing activity.
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