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Preliminary pharmacological investigations on camel urine (Camelus dromedarius)

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Author(s): Salwa M. E. Khogali, | Samia .H. Abdrahman Baragob, | A. E. A | Elhassan A. M

Journal: Research Opinions in Animal & Veterinary Sciences
ISSN 2221-1896

Volume: 1;
Issue: 6;
Start page: 379;
Date: 2011;
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Keywords: Pharmacological | Investigation | Camel | Urine

ABSTRACT
Pharmacological effects of camel urine (CU), its protein precipitate (PP), diluted urine (DU) and chloroformic extract (CE) were investigated. The PP inhibited the spontaneous movements of the isolated rat duodenum at a dose rate of 0.1ml/bath. Diluted female camel urine (0.4 ml/bath) or its protein precipitate (0.8 ml/bath) on rat fundus and rabbit jejunum revealed serotonin like effect which was antagonized by serotonin blocker cypohyptadine (0.2 ml /bath). In addition crude female camel urine produced transient relaxation on rabbit jejunum followed by increased contraction on first washing. chloroformic extract produced no effect on rat duodenum, fundus and rabbit jejunum, whereas rabbit and chick rectum showed slight changes in the frequency and amplitude contractions.
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