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The presence of promatrix metalloproteinase-3 and its relation with different categories of coal workers' pneumoconiosis

Author(s): Remzi Altin | Levent Kart | İshak Tekin | Ferah Armutcu | Meltem Tor | Tacettin Örnek

Journal: Mediators of Inflammation
ISSN 0962-9351

Volume: 13;
Issue: 2;
Start page: 105;
Date: 1992;
Original page

Keywords: Matrix metalloproteinases | Promatrix metalloproteinase-3 | Coal miners | Pneumoconiosis.

Extracellular matrix formation (ECM) and remodeling are critical events related to the pathogenesis of pulmonary fibrosis. Matrix metalloproteinases play an essential role in degrading and remodeling the ECM. In this study, we tried to show the presence and correlation of promatrix metalloproteinase-3 (proMMP-3) (the inactive form of metalloproteinase-3) levels in coal workers' pneumoconiosis (CWP) with different categories.

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