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Prevalence of chronic kidney disease in HIV positive patients in Lagos, south-west Nigeria

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Author(s): Theophilus Umeizudike | Monica Mabayoje | Charles Okany | Fatima Abdulkareem | Adekunle Adeyomoye | Njideka Okubadejo | Ikechi Okpechi

Journal: Nephrology Reviews
ISSN 2035-8261

Volume: 4;
Issue: 1;
Start page: e5;
Date: 2012;
Original page

Keywords: chronic kidney disease | HIV | macroalbuminuria | albumin-creatinine ratio | kidney biopsy

ABSTRACT
The human immunodeficiency virus (HIV) pandemic is one of the leading causes of death in the developing world. Chronic kidney disease (CKD) and end-stage renal disease (ESRD) associated with HIV are major causes of morbidity and mortality in HIV-positive patients. This cross-sectional study was conducted to determine the prevalence and risk factors of CKD in HIV-positive, antiretroviral naïve patients at a single HIV clinic in Lagos, Nigeria. Of 402 patients, CKD was observed in 23.5% while among 146 controls, CKD was detected in 5.5% (odds ratio (OR) 5.34 [95% CI 2.4-12.2]; P
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