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Prevalence of IgG and IgM anti-Toxoplasma antibodies in patients with HIV and acquired immunodeficiency syndrome (AIDS)

Author(s): Galván Ramírez María de la Luz | Valdez Alvarado Virginia | Vargas Gutierrez Gustavo | Jiménez González Octavio | García Cosio Carlos | Vielma Sandoval Marcos

Journal: Revista da Sociedade Brasileira de Medicina Tropical
ISSN 0037-8682

Volume: 30;
Issue: 6;
Start page: 465;
Date: 1997;
Original page

Keywords: Anti-Toxoplasma antibodies | AIDS | HIV | Toxoplasmosis

With the emergence of the human immunodeficiency virus (HIV), in patients with acquired immunodeficiency syndrome (AIDS), Toxoplasma gondii has arisen as an important opportunist pathogenic agent, especcially in the central nervous system, being the most common cause of intracerebral lesions. The incidence of Toxoplasma gondii in HIV-infected patients depends principally on the existence of latent Toxoplasma parasitosis in the population affected. Through the enzyme-linked immunosorbent assay (ELISA), IgG and IgM anti-Toxoplasma antibodies were found in 92 patients of which 46 (50.0%) were IgG seropositive, and only one case (1.0%) had IgM antibodies.Of the 92 patients: 53 were HIV seropositives and 39 had AIDS. The detection and monitoring of anti-Toxoplasma antibodies in HIV patients is essential, since in this group there is a high percentage risk of developing cerebral toxoplasmosis, which is the second cause of death in this type of patients.
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