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Prevalence of rotavirus diarrhoea among children hospitalized in a tertiary care hospital in Western India

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Author(s): Sanjay C. Chavan | Sharad Agarkhedkar | Dipali S. Chavan | RP. Nagdawane | Smita Singhania

Journal: International Journal of Pharmacy and Biomedical Sciences
ISSN 0976-5263

Volume: 04;
Issue: 01;
Start page: 04;
Date: 2013;
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Keywords: Reoviridae | Virus infection | Gastroenteritis | Public health problems | ELISA | Maharashtra

ABSTRACT
Globally, rotavirus is the most common cause of severe diarrhoea in children. In India, rotavirus accounts for 20-40% of childhood acute diarrhoeas. A total of 150 cases of acute diarrhoea in children below 5 years of age admitted at tertiary care hospital in suburban area of industrial town of western Maharashtra, India were included in the study. Stool samples were taken for all the cases and screened for rotavirus infection by ELISA using a commercial kit. Out of 150 samples tested, 57 were positive for rotavirus infection. The peak occurrence of rotavirus infection was found between 7-12 months followed closely by 13-24 months of age group. Detection rate of rotavirus was low in 0-6 months and 25-60 months of age group. The prevalence of rotavirus causing diarrhoea in the present study was found to be 38%. The overall occurrence of rotavirus positive cases of diarrhoea was more amongst male than the female patients. However, percentage of rotavirus positive cases amongst the male and female patients was almost similar. Statistically significant (P

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