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Probabilistic Risk Assessment of Cancer from Exposure Inorganic Arsenic in Duplicate Food by Villagers in Ronphibun, Thailand

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Author(s): Piyawat Saipan

Journal: EnvironmentAsia
ISSN 1906-1714

Volume: 3;
Issue: 2;
Start page: 54;
Date: 2010;
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Keywords: probabilistic risk assessment | inorganic arsenic | duplicate food | Ronphibun district

ABSTRACT
Ronphibun district is a district in Nakorn Si Thammarat province, within southern Thailand. This district is the site of several former tin mines that were in operation 100 years ago. Arsenic contamination caused by past mining activities remains in the area. The specific purpose of this study was conducted to assess cancer risk in people living within Ronphibun district from exposure to inorganic arsenic via duplicate food using probabilistic risk assessment. A hundred and fifty duplicate food samples were collected from participants. Inorganic arsenic concentrations are determined by hydride generation atomic absorption spectrometry. Inorganic arsenic concentrations in duplicate food ranged from 0.16 to 0.42 μg/g dry weight. The probabilistic carcinogenic risk levels were 6.76 x 10-4 and 1.74 x 10-3 based on the 50th and 95th percentile, respectively. Risk values for people in Ronphibun from exposure to inorganic arsenic remained higher than the acceptable target risk. Sensitivity analysis indicted that exposure duration and concentrations of arsenic in food were the two most influential of cancer risk estimates.
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