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Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut

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Author(s): Gildas K. Gbassi | Thierry Vandamme

Journal: Pharmaceutics
ISSN 1999-4923

Volume: 4;
Issue: 1;
Start page: 149;
Date: 2012;
Original page

Keywords: biomaterials | microencapsulation | probiotics | protective device | artificial media | cells release

ABSTRACT
Probiotic encapsulation technology (PET) has the potential to protect microorgansisms and to deliver them into the gut. Because of the promising preclinical and clinical results, probiotics have been incorporated into a range of products. However, there are still many challenges to overcome with respect to the microencapsulation process and the conditions prevailing in the gut. This paper reviews the methodological approach of probiotics encapsulation including biomaterials selection, choice of appropriate technology, in vitro release studies of encapsulated probiotics, and highlights the challenges to be overcome in this area.
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